RELATIONSHIP BETWEEN CLINICAL STAGE, TYPE OF SURGERY, AND TYPE OF CHEMOTHERAPY WITH 5-YEAR SURVIVAL RATE IN COLORECTAL CANCER PATIENTS WHO RECEIVED CHEMOTHERAPY

Treatment for colorectal cancer (CRC) patients are chemotherapy and/or surgery, with the surgical approach and chemotherapy regimens are varied. This study aims to analyze the relationship between clinical stage, type of surgery, and type of chemotherapy with 5-year survival rates in colorectal cancer patients treated with chemotherapy. This retrospective cohort study was conducted at Dr. Saiful Anwar Malang Regional General Hospital in CRC patients treated from 2017 to 2022. All data were obtained from medical records. This study included 220 patients who met the inclusion and exclusion criteria. Most patients were over 50 years old and male gender. The most common clinical stage was IV A, typically involving emergency surgery and FOLFIRI chemotherapy. The majority of patients presented at late stages, resulting in a poor prognosis. Stage IIA patients had the highest 5-year survival rate (69.7%), while stage IVB patients had the lowest (41.2%). Patients who underwent non-emergency surgery had a higher 5-year survival rate (54.4%) compared to those who had emergency surgery (44.4%). Surgery type significantly impacted 5-year survival, with emergency surgery associated with a 3.727 times lower survival rate compared to non-emergency surgery. There was no relationship between the clinical stage of colorectal cancer patients at our center and their 5-year survival rate. However, the type of surgery significantly affected survival rates. The type of chemotherapy did not impact the 5-year survival rate. Overall, the type of surgery was the most important factor for the 5-year survival rate of colorectal cancer patients undergoing chemotherapy at our center.