General Medicine (ISSN:1311-1817)

This study aimed to evaluate the bonding strength of polyether ether ketone (PEEK) posts and cores to root dentin after various surface treatments: Er:YAG laser (with and without contact), CO₂ laser (without contact), and sandblasting. Thirty-two single-rooted premolars were decoronated and endodontically treated. Custom CAD/CAM PEEK posts and cores were fabricated and divided into four groups (n=8): Group 1 – sandblasted with 50 μm Al₂O₃; Group 2 – Er:YAG laser in contact; Group 3 – Er:YAG laser non-contact; Group 4 – CO₂ laser non-contact. All posts were cemented with dual-c

This case series reports outcomes of 26 patients who underwent laparoscopic cholecystectomy for cholelithiasis in 2023 at a single center. The objective was to evaluate the incidence of bile duct injury based on surgical technique—3-port versus 4-port approach—and to assess the influence of additional procedures and diagnoses on outcomes. A retrospective analysis was conducted on 26 patients who underwent laparoscopic cholecystectomy between January and December 2023. Patients were divided into two groups: 16 underwent the 3-port technique, and 10 underwent the 4-port technique. Data were

This study aimed to evaluate the role of serum ferritin as a prognostic biomarker in assessing disease severity among patients diagnosed with dengue fever. A cross-sectional study was conducted at Lahore Medical & Dental College/Ghurki Trust Teaching Hospital, Pakistan, from April to September 2024. A total of 180 adult dengue-confirmed patients (NS1 antigen or IgM positive) were enrolled. Patients were classified into three severity grades based on WHO 2009 criteria: Grade A (no warning signs), Grade B (with warning signs), and Grade C (severe dengue). Serum ferritin, platelet count, and hema

The contribution of HPV and EBV to bladder cancer has been controversial. Recent studies suggest a significant association between HPV and bladder cancer; however, more investigations are needed to explore the possible role of EBV as well. This study aims to investigate the potential role of human papillomavirus (HPV) and Epstein–Barr virus (EBV) in the development of bladder cancer. We will first assess the prevalence of these two viruses and then their coinfection. Second, we will correlate their prevalence with clinical and pathological data, considering their mechanisms in cancer. HPV a

Breast cancer represents the most frequently diagnosed malignancy in women globally, with oncogenic viruses contributing to 20-50% of cases. Human papillomavirus (HPV) and human herpesvirus 8 (HHV-8) have been implicated in various cancers, but their co-infection patterns in breast cancer remain poorly characterized, particularly in North African populations. This study aimed to investigate the molecular characterization and clinicopathological associations of HPV and HHV-8 co-infection in Moroccan breast cancer patients. Ninety fresh tissue specimens were analyzed, including 60 histopathologi