General Medicine (ISSN:1311-1817) is a monthly peer-reviewed scopus indexed journal from 2001 to Present. It Publisher Meditsinski Universitet - Sofia. General Medicine is committed gathering and disseminating excellent research achievements, Inspiring medical innovation and Promoting the Development of Disciplines. GM welcomes all types of medical journal includes medicine, pharmacy, bio-chemistry, psychology,Public health etc.
Breast fibroadenoma is one of the most common benign tumors among females less than 30 years old. Females are adopting treatment using alternative methods rather than surgical treatment for breast fibroadenoma. The current study examined the effectiveness of castor oil in treating breast fibroadenoma. A case study design was utilized. A female diagnosed with breast fibroadenoma used castor oil for more than 2 months. A breast ultrasound was obtained before and after using castor oil on the site of breast fibroadenoma to test the effectiveness of the new treatment. The results of this study ind
The therapeutic mechanisms of the herbal formula Juru-5 in managing type 2 diabetes mellitus (T2DM) were investigated through a systematic pharmacology approach and molecular docking techniques. Active compounds and their targets were identified using TCMSP, BATMAN-TCM, and other databases, while T2DM-related targets were obtained from GeneCards, OMIM, TTD, and DrugBank. The analysis of overlapping targets between Juru-5 and T2DM was performed using PPI networks, GO, and KEGG pathway enrichment. Validation of key compound-target interactions was conducted through molecular docking studies. In
Lifestyle behaviours influence overall and central adiposity, yet conventional measures such as BMI may not fully capture lifestyle-related variations in body shape, necessitating evaluation of waist-based indices. To determine the relationship between body composition indices (including BMI, ABSI, BRI, Conicity Index) and lifestyle among adults. A hospital-based analytical cross-sectional study was conducted among 100 adults, recording demographics, standardized anthropometry (height, weight, waist circumference) and calculating BMI, ABSI (with z-scores), BRI and Conicity Index. Lifestyle was
The extensive use of pesticides in agricultural practices poses significant risks to human health due to the potential presence of chemical residues. Chronic exposure to pesticide residues has been associated with various adverse health effects, highlighting the importance of ensuring food safety, particularly for widely consumed vegetables such as tomatoes. Concerns have arisen regarding possible health effects linked to pesticide exposure, particularly from abamectin, one of the pesticides frequently applied by local farmers. However, a validated method to detect the residue of pesticides in
Depression is a major global health problem, and current treatments are often limited by delayed therapeutic effects, side effects, and incomplete response, particularly in moderate to severe cases. Increasing evidence highlights the role of the gut–brain axis in mood regulation, where gut microbiota influence immune, inflammatory, and neurochemical pathways. In this context, probiotics have emerged as a promising adjunctive approach, as they may modulate gut microbiota, regulate immune responses, and influence neuroactive compounds, potentially reducing depressive symptom severity. However,