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[This article belongs to Volume - 25, Issue - 06]

A Cross-sectional study on factors influencing long term survival among HIV patients taking ART in a Government tertiary care hospital.

HIV infection, as a persistent chronic condition, leads to both morbidity and mortality and antiretroviral therapy (ART) contributes to enhanced survival and overall well being of people living with HIV. Lack of adherence to antiretroviral therapy has a direct relationship with CD4 counts. Hence, the present study aimed to study the clinical characteristics and outcomes of individuals living with HIV for duration of at least 10 years, during the antiretroviral therapy (ART) era. A descriptive cross-sectional study was carried out at the Government tertiary care hospital in the year 2022. 50 persons living with HIV for the past 10 years were included. Data were collected regarding the demographic characteristics, clinical and treatment history. Data analysis was done by SPSS version 17. The proportion of female patients (56%) was higher than male patients (44%). At the end of the mean 13.97 years of living with HIV (PLHIV), 98% of patients who maintained a high compliance rate of 95% with antiretroviral therapy (ART) were found to be asymptomatic. These results demonstrate the importance of adhering to ART and its positive impact on the long-term health outcomes of PLHIV, particularly in females. However, it also underscores the significance of consistent medication adherence to achieve optimal results and prevent disease progression. TB co-infection and lower CD4 counts have significant impact on the outcome of PLHIV. A high compliance rate and absence of symptoms demonstrate the importance of adherence to ART and its positive impact on the long-term health outcomes of PLHIV.