ANTIHYPERTENSIVE MEDICATION PRESCRIPTION PRACTICES IN HYPERTENSIVE PATIENTS WITH NON-INSULIN DEPENDENT DIABETES MELLITUS

The current study aims to investigate the antihypertensive medication prescription practices in hypertensive patients with non-insulin dependent diabetes mellitus in the countries of Bangladesh and Pakistan. The cross-sectional study was conducted in multi-settings of Pakistan and Bangladesh involving Medicine Departments over a period of six months, beginning in December 2023 and ending in May 2024. There were 640 study participants. To enroll the sample, a technique known as consecutive randomization was utilized. Outpatients with hypertension who have non-insulin dependent diabetes mellitus were included in the study for inclusion criteria. The information regarding socio-demographic characteristics and the antihypertensive medications that were provided to hypertensive patients with diabetes mellitus was gathered through the use of a questionnaire that was devised by the researchers themselves. In order to conduct the statistical analysis, version 26 of SPSS was utilized. In the presentation of the data, frequencies and percentages were used. Finding shows that 78% patients belong to Bangladesh were male, while 22% were female. Whereas Pakistan, the average age of patients was 51.9 years, with a standard deviation of 9.1 years. The p-value for this comparison was significant. As part of the study, the anti-hypertensive therapy status in the Bangladeshi population with single therapy was found to be 85%, while the fixed dose combination was found to be 42%. Similarly, in the Pakistani population, the single therapy was found to be 79.6%, and the fixed dose combination was found to be 12.9%. This study helped Pakistani and Bangladeshi authorities develop evidence-based prescribing patterns, physician training on standard guidelines, pharmacist recruiting for therapy, and on-prescription rationality testing to improve patient health outcomes.