Bacteriological Evaluation of the Antibacterial Efficacy of Chemo-Mechanical Caries Removal Using Brix 3000 and Carisolv on Carious First Permanent Molars in Children.

To evaluate the effect of brix 3000 and carisolv on the bacteria present within dentin carious lesions. The study sample consisted of 30 permanent first molars with Class I carious lesions in 40 children aged between 7 and 9 years. Samples were divided into two main groups according to the treatment method (Brix 3000, Carisolv). The colony-forming units (CFU) were investigated before and after caries excavation in each group. Data were analyzed using the Wilcoxon signed rank and Mann-Whitney U tests. The results showed that both Brix 3000 and Carisolv reduced the number of bacterial colonies in the carious dentin with statistically significant differences (p<0.05) when comparing two stages in the group of each material (before caries excavation - after caries excavation). The results also showed that Brix 3000 reduced the number of bacterial colonies to a greater extent than Carisolv, with a statistically significant difference (p<0.05), as the mean decrease in the number of bacterial colonies for both the Brix 3000 and Carisolv groups was (2.08, 1.64 log cycle, respectively). Brix 3000 effectively eliminated cariogenic bacteria and reduced bacterial colony counts more than carisolv.