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[This article belongs to Volume - 26, Issue - 01]

Evaluation of the analgesic effect of five intra-articular ozone injections of knee osteoarthritis

Knee osteoarthritis is a degenerative disease of the knee joint. It is more common in people older than 40 years. Symptoms may include joint pain, tenderness, stiffness, locking, and sometimes an effusion. A variety of causes—hereditary, developmental, metabolic, and mechanical—may initiate processes leading to loss of cartilage. OA is a top cause of disability in older people. The goal of treatment in OA is to reduce pain and improve function. There is no cure for the disease, but some treatments attempt to slow disease progress. Intraarticular ozone injections in knee osteoarthritis represent a complementary treatment method which provides pain relief, decongestion, subsidence of bruises (hematomas), a reduction in temperature and an improvement in motility. Intraarticular ozone injection is increasingly being applied. To evaluate the pain killing effect of 4 ozone-oxygen intra-articular injections of knee joint osteoarthritis. It is a prospective, randomized clinical trial, done on 30 knee joints, all patient were with history of OA of knee joint & suffering from long standing pain & they have long history of medical therapy. After taking patient consent, 5 weekly sessions intraarticular 5 ml (25 μg/ ml) ozone injections were done under complete aseptic technique. Numerical Analog Pain score has been assessed and recorded before each session. Patients responded well to intraarticular ozone injection with a success rate of 86.66%. It is found that there is significant difference between different sessions and the p-value was below 0.05 in all the time. Intraarticular ozone injection has significant progressive effect in reducing pain in knee joint osteoarthritis for 4 successive sessions.