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[This article belongs to Volume - 26, Issue - 03]

INVESTIGATING THE INTERACTION BETWEEN DOPAMINE RECEPTORS AND ANTIBODIES AGAINST GROUP A STREPTOCOCCUS WITH A RANGE OF DIETARY ANTIGENS

Humans are the only animals that may contract Group A streptococcus (GAS), also referred to as Streptococcus pyogenes. Mild diseases are impetigo, scarlet fever, and pharyngitis. Dopamine 1 and 2 (D1 and D2) receptors as well as available markers for neuropsychiatric disease assessment were covered in the study. Nevertheless, these antibodies were found in study subjects who were in good health. Since we had shown significant cross-reactivity between food antigens, human tissues, and pathogens in our earlier research, the aim of this study was to investigate whether or not there is cross-reactivity between GAS, dopamine D1, D2 receptors, and regularly consumed foods. Cross-reactivity between food and tissue antigens has been shown in earlier studies. We examined antibodies against GAS, D1, and D2 receptors against the antigens of one hundred distinct meals using the ELISA method. There was a significant amount of cross-reactivity observed between anti-GAS antibodies and 17/100 foods, anti-D1 antibodies and 26/100 foods, and anti-GAS antibodies and 47/100 foods. According to our research, patients who have GAS, D1, and D2 antibodies in their blood may not actually have these conditions at all, but are instead just carrying safe antibodies against food antigens. This suggests that the presence of these antibodies in blood may also make it more difficult to measure these biomarkers accurately.