THE CORRELATION BETWEEN SERUM UREA, CREATININE AND DIABETES MELLITUS TYPE II IN JORDAN

Type II Diabetes Mellitus (T2DM) is a significant health concern in Jordan due to its association with hyperglycemia and the potential development of Nephropathy. The research is conducted to evaluate the correlation between serum urea and creatinine levels in patients with T2DM and the development of Nephropathy in patients at Prince Hamza Hospital located in Jordan. A descriptive cross-sectional study conducted at Prince Hamza Hospital in Jordan from September 2023 to March 2024, that include a secondary data from 299 patients with type 2 diabetes mellitus were collected retrospectively from medical records. Serum urea, creatinine, and HbA1c levels were measured using Alinity or Beckman-Coulter instruments. Statistical analysis was performed using SPSS and chi-square tests. The study included 299 patients with type 2 diabetes, mostly female (56.9%) and over 60 years old (46.2%). Chi-square analysis showed significant associations between HbA1c and age groups categories, for good control, suboptimal and poor control (p=0.015, p=0.001, p=0.015) respectively. HbA1c with serum urea was (p<0.001), with creatinine (p<0.001) levels, and with significant on kidneys was (p-value was <0.001, 0.018, and <0.001) respectively. The findings showed a significant positive correlation between serum urea, creatinine, and T2DM in the study population. This highlights the importance of monitoring these biomarkers in the management of individuals with type 2 diabetes.