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[This article belongs to Volume - 26, Issue - 01]

The Prevalence and Management of Vitamin D Deficiency in People with Type Two Diabetes: Systematic Review

Vitamin D is an essential micronutrient that has been associated with the pathogenesis of type 2 diabetes. This review aimed to assess the prevalence and management of Vitamin D deficiency in patients with type 2 diabetes mellitus. We searched PubMed, Scopus, Web of knowledge the Cochrane Library, and Embase databases from January 2015 to November 2023. The search key terms included “Vitamin D deficiency”, “Cholecalciferol”, “Treatment “and “Diabetes” or “T2DM”. Out of the 1471 articles retrieved, 42 full texts were screened and, 10 randomized controlled trials were included in the meta-analysis. The review showed that vitamin D deficiency is highly prevalent in patients with T2DM worldwide. No significant effects were evident of vitamin D supplementation on fasting blood glucose and HbA1c, odd ratio, -0.49, 95% CI, -5.25-4.27, and odd ratio, 0.03, 95% CI, -0.13-0.18 respectively. No significant effects were evident regarding glycemic control. High quality randomized controlled trials are required.